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This is why we strongly recommend: Using a cycling protocol (periods of use followed by planned breaks) rather than continuous, indefinite use

Enhancing PI3K/Akt signaling can protect against oxidative damage in IBD

Lower fasting blood sugar levels and body mass index in patients with diabetes mellitus

Pharmacokinetics of equol, a soy isoflavone metabolite, changes with the form of equol (dietary versus intestinal production) in ovariectomized rats

Taking steps like avoiding common trigger foods, eating smaller meals, eating your last meal several hours before bedtime, and elevating the head of your bed by at least 8 inches are great places to start to see if your symptoms improve